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The Encyclopedia of DNA Elements (ENCODE) consortium aims to identify all functional elements in the human genome sequence. These elements include genomic regions bound by transcription factors (TFs), occupied by nucleosomes, occupied by nucleosomes with modified histones, hypersensitive to cleavage of DNase I, etc. We organize the on-going analysis results of TF binding data in the web accessible repository factorbook.org.

Chromatin Immunoprecipitation (ChIP-seq) is the experimental technique used to generate TF-binding data, and the genomic regions bound by TFs are called ChIP-seq peaks. The transcription factor binding sites (TFBS) are the positions on the genomic DNA bound by TFs and tend to be located around the summits of ChIP-seq peaks. Below is a matrix of all ENCODE TF ChIP-seq datasets, arranged by cell lines. Click the TF name of interest to access individual pages.


Citation: J Wang, J Zhuang, S Iyer, XY Lin, et al. Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors. Genome Research 22 (9), 1798-1812


Protein Family
Type              
Cellline»
«Factor
A549
AG04449
AG04450
AG09309
AG09319
AG10803
AoAF
BE2_C
BJ
Caco-2
ECC-1
FetalPBDE
GM06990
GM10847
GM12864
GM12865
GM12872
GM12873
GM12874
GM12875
GM12878
GM12891
GM12892
GM15510
GM18505
GM18526
GM18951
GM19099
GM19193
H1-hESC
HA-sp
HAc
HBMEC
HCFaa
HCM
HCPEpiC
HCT-116
HEEpiC
HEK293
HeLa-S3
HepG2
HFF-Myc
HMEC
HMF
HPAF
HPF
HRE
HRPEpiC
HSMM
HSMMtube
HUVEC
K562
MCF-7
MCF10A-Er-Src
NB4
NH-A
NHDF-Ad
NHEK
NHLF
NT2-D1
Osteobl
PANC-1
PBDE
PFSK-1
Raji
SAEC
SH-SY5Y
SK-N-MC
SK-N-SH
SK-N-SH_RA
T-47D
T-REx-HEK293
U2OS
U87
WERI-Rb-1
WI-38
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