GATA3

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GATA binding protein 3
GATA3
PDBsearch GATA3
HGNC(alias)GATA3 (HDR)
Gene CardGATA3
Entrez2625
RefSeqNM_001002295
UniProtP23771
UCSCBrowser view
WikipediaGATA3
Protein FamilyGlucocorticoid receptor-like (DNA-binding domain)
TypePol II TF
Ensembl Exp.n/a

Function

This gene encodes a member of the GATA family of zinc-finger transcription factors named for the consensus nucleotide sequence (5'-AGATAG-3') they bind in the promoter regions of target genes. GATA-3 plays important roles in the regulation of T-cell development and in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.

ENCODE ChIP-seq Datasets

Indicated in the matrix are the numbers of datasets specified by lab and cell line; when the number is greater than 1, multiple ChIP-seq experiments have been performed, some upon treatments. Click the numbers to download the data files on ChIP-seq peaks, alignments, etc.

+/-
HudsonAlpha
USC
SH-SY5Y 1
T-47D 1


Average Profiles of Modified Histones around the Summit of ChIP-seq Peaks

No Available Data

Average Profiles of Nucleosomes around the Summit of ChIP-seq Peaks

No Available Data

Motifs Enriched in the Top 500 ChIP-seq Peaks

The sequences of the top 500 TF ChIP-seq peaks were used to identify enriched motifs de novo, using the MEME-ChIP suite of tools. Five motifs are reported (M1 to M5), with motif name, sequence logo, and number of peaks out of the top 500 peaks that contain a site for the motif. The motifs are then used to scan the entire set of ChIP-seq peaks and the two flanking (control) regions using the FIMO tool, and two quantities are reported for bins of peaks sorted by their ChIP-seq q-values: percentage of the peaks that contain a site for the motif, and the distribution of the distances of the motif site to the summit of the peak.

Select MotifCell Line:   Lab:   Protocol:   Treatment:   Antibody:  



Binding of Other Transcription Factors or Histone Marks at the GATA3 Peaks

Select HeatmapLab:   Cellline:  

  • Comparison with the GATA3 peaks in T47D cells generated by HAIB