SMAD5

The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. RefSeq, Feb 2014
Mothers against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SMAD5 gene. SMAD5, as its name describes, is a homolog of the Drosophila gene: "Mothers against decapentaplegic".wikipedia

SMAD5


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Gene Card search
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RefSeq search
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Wikipedia SMAD5

Average Profiles of Modified Histones around the Summit of ChIP-seq Peaks

GM12878 - Myers - ENCSR251OVJ

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K562 - Myers - ENCSR000FCD

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Legend

Proximal:
  • H2AFZ
  • H3K27ac
  • H3K27me3
  • H3K36me3
  • H3K4me1
  • H3K4me2
  • H3K4me3
  • H3K79me2
  • H3K9ac
  • H3K9me1
  • H3K9me3
  • H4K20me1
Distal:
  • H2AFZ
  • H3K27ac
  • H3K27me3
  • H3K36me3
  • H3K4me1
  • H3K4me2
  • H3K4me3
  • H3K79me2
  • H3K9ac
  • H3K9me1
  • H3K9me3
  • H4K20me1

Notes

Average histone modification profiles are shown for the [-2 kb, +2 kb] window around the summits of TF ChIP-seq peaks. Profile are shown separately for peaks that are proximal ([-1 kb, +1 kb]; ending in '-p') to an annotated transcript start site (TSS) and for peaks that are distal (>1 kb; ending in '-d') to all annotated TSS. TSS-proximal profiles are arranged such that the nearest transcript proceeds towards the right.

Motifs Enriched in the Top 500 ChIP-seq Peaks

GM12878 - Myers - ENCSR251OVJ

1.
13 / 500
1.4e-40
TTGCGTGGCGCCTTGCCGCCGGTGGACTT
small heat map img p-value: 0.00
pct_center: 0.19
pct_ratio: 0.61
2.
107 / 500
4.1e-36
GAAGAGAAAGA
small heat map img p-value: 0.35
pct_center: 0.22
pct_ratio: 0.43
3.
43 / 500
4.1e-23
CAAGATGGCGG
small heat map img p-value: 0.00
pct_center: 0.14
pct_ratio: 0.73
4.
7 / 500
8.1e-22
AAGGGTCTGGGTAAGGGAGGCGCCAAGCG
small heat map img p-value: 0.25
pct_center: 0.22
pct_ratio: 0.54
5.
10 / 500
1.8e-12
AAATGTGGGAAACTCGACTGCATAATTTGT
small heat map img p-value: 0.42
pct_center: 0.03
pct_ratio: 0.43
MEME output

Notes

The top 500 TF ChIP-seq peaks were used to identify enriched motifs de novo, using the MEME-ChIP suite of tools. Up to five motifs are reported (1 to 5) if they meet the criteria defined by our pipeline.

K562 - Myers - ENCSR000FCD

1.
53 / 500
4.9e-27
CAAGATGGCGGCGGC
small heat map img p-value: 0.00
pct_center: 0.19
pct_ratio: 0.69
2.
185 / 500
9.5e-30
GGGCAGCAGAGGAGGAGGGGA
small heat map img p-value: 0.00
pct_center: 0.68
pct_ratio: 0.56
3.
5 / 500
0.0038
GTGATGCCCTGGATGTTATCGCGCA
small heat map img p-value: 0.54
pct_center: 0.05
pct_ratio: 0.50
4.
16 / 500
0.0000037
TTTTTTTTAATTTTTTTTCGGTTTTGCAT
small heat map img p-value: 0.95
pct_center: 0.06
pct_ratio: 0.29
5.
9 / 500
0.0032
TGGAGTGCAGTGGCGCGAACTCGGCTCAC
small heat map img p-value: 1.00
pct_center: 0.19
pct_ratio: 0.49
MEME output

Notes

The top 500 TF ChIP-seq peaks were used to identify enriched motifs de novo, using the MEME-ChIP suite of tools. Up to five motifs are reported (1 to 5) if they meet the criteria defined by our pipeline.

Binding of other histone marks at SMAD5 peaks

GM12878 - Myers - ENCSR251OVJ

GM12878
Myers
H3K9ac
ENCSR000AKH
r=0.36

small heat map img

GM12878
Myers
H3K27ac
ENCSR000AKC
r=0.32

small heat map img

GM12878
Myers
H3K4me3
ENCSR000DRY
r=0.32

small heat map img

GM12878
Myers
H3K4me3
ENCSR000AKA
r=0.30

small heat map img

GM12878
Myers
H2AFZ
ENCSR000AOV
r=0.25

small heat map img

GM12878
Myers
H3K4me2
ENCSR000AKG
r=0.24

small heat map img

GM12878
Myers
H3K79me2
ENCSR000AOW
r=0.20

small heat map img

GM12878
Myers
H4K20me1
ENCSR000AKI
r=0.06

small heat map img

GM12878
Myers
H3K9me3
ENCSR000AOX
r=0.06

small heat map img

GM12878
Myers
H3K4me1
ENCSR000AKF
r=0.06

small heat map img

GM12878
Myers
H3K36me3
ENCSR000DRW
r=0.05

small heat map img

GM12878
Myers
H3K36me3
ENCSR000AKE
r=0.01

small heat map img

GM12878
Myers
H3K27me3
ENCSR000AKD
r=-0.02

small heat map img

GM12878
Myers
H3K27me3
ENCSR000DRX
r=-0.03

small heat map img
0 (download )

K562 - Myers - ENCSR000FCD

K562
Myers
H3K9ac
ENCSR000AKV
r=0.36

small heat map img

K562
Myers
H3K4me3
ENCSR000AKU
r=0.36

small heat map img

K562
Myers
H3K4me3
ENCSR000DWD
r=0.34

small heat map img

K562
Myers
H3K4me2
ENCSR000AKT
r=0.33

small heat map img

K562
Myers
H3K27ac
ENCSR000AKP
r=0.33

small heat map img

K562
Myers
H3K9ac
ENCSR000EVZ
r=0.33

small heat map img

K562
Myers
H3K4me3
ENCSR000EWA
r=0.32

small heat map img

K562
Myers
H2AFZ
ENCSR000APC
r=0.22

small heat map img

K562
Myers
H3K79me2
ENCSR000APD
r=0.21

small heat map img

K562
Myers
H4K20me1
ENCSR000AKX
r=0.14

small heat map img

K562
Myers
H3K4me1
ENCSR000EWC
r=0.10

small heat map img

K562
Myers
H3K36me3
ENCSR000AKR
r=0.04

small heat map img

K562
Myers
H3K9me1
ENCSR000AKW
r=0.02

small heat map img

K562
Myers
H3K9me3
ENCSR000APE
r=0.01

small heat map img

K562
Myers
H3K4me1
ENCSR000AKS
r=0.01

small heat map img

K562
Myers
H3K27me3
ENCSR000AKQ
r=0.00

small heat map img

K562
Myers
H3K27me3
ENCSR000DWC
r=-0.00

small heat map img

K562
Myers
H3K36me3
ENCSR000DWB
r=-0.00

small heat map img

K562
Myers
H3K27me3
ENCSR000EWB
r=-0.06

small heat map img
0 (download )

Notes

ChIP-seq peaks (left to right in the heatmap) for the current TF are sorted by descending TF ChIP-seq signal. The ChIP-seq signals of histone modifications are plotted for the genomic regions that correspond to the peaks of the current TF in the same order. The Pearson correlation coefficient (r) of the histone modification ChIP-seq signal with the TF ChIP-seq signal is shown.

legend
Binding of other TFs at SMAD5 peaks

GM12878 - Myers - ENCSR251OVJ

GM12878
Myers
POLR2A
ENCSR000EAD
r=0.74

small heat map img

GM12878
Myers
POLR2A
ENCSR000EYW
r=0.68

small heat map img

GM12878
Myers
POLR2A
ENCSR000DKT
r=0.65

small heat map img

GM12878
Myers
POLR2A
ENCSR000BGD
r=0.60

small heat map img

GM12878
Myers
PML
ENCSR000BQM
r=0.59

small heat map img

GM12878
Myers
POU2F2
ENCSR000BGP
r=0.58

small heat map img

GM12878
Myers
KAT2A
ENCSR000DNO
r=0.48

small heat map img

GM12878
Myers
CHD1
ENCSR000DZE
r=0.47

small heat map img

GM12878
Myers
TBL1XR1
ENCSR000DYZ
r=0.46

small heat map img

GM12878
Myers
NFATC1
ENCSR000BQL
r=0.45

small heat map img

GM12878
Myers
TBP
ENCSR000DZZ
r=0.44

small heat map img

GM12878
Myers
RELA
ENCSR000EAG
r=0.44

small heat map img

GM12878
Myers
RCOR1
ENCSR000DZC
r=0.43

small heat map img

GM12878
Myers
STAT5A
ENCSR000BQZ
r=0.40

small heat map img

GM12878
Myers
STAT1
ENCSR000DZM
r=0.39

small heat map img

GM12878
Myers
ESRRA
ENCSR000DYQ
r=0.39

small heat map img

GM12878
Myers
MAX
ENCSR000DZF
r=0.39

small heat map img

GM12878
Myers
TAF1
ENCSR000BGS
r=0.38

small heat map img

GM12878
Myers
ATF2
ENCSR000BQK
r=0.38

small heat map img

GM12878
Myers
MXI1
ENCSR000DZI
r=0.38

small heat map img

GM12878
Myers
MTA3
ENCSR000BRH
r=0.37

small heat map img

GM12878
Myers
ELK1
ENCSR000DZB
r=0.37

small heat map img

GM12878
Myers
CUX1
ENCSR000DYR
r=0.37

small heat map img

GM12878
Myers
NFIC
ENCSR000BRN
r=0.37

small heat map img

GM12878
Myers
FOXM1
ENCSR000BRU
r=0.37

small heat map img

GM12878
Myers
MAFK
ENCSR000DYV
r=0.36

small heat map img

GM12878
Myers
BCL3
ENCSR000BNQ
r=0.36

small heat map img

GM12878
Myers
RUNX3
ENCSR000BRI
r=0.36

small heat map img

GM12878
Myers
SIN3A
ENCSR000DYX
r=0.35

small heat map img

GM12878
Myers
SMC3
ENCSR000DZP
r=0.34

small heat map img

GM12878
Myers
CEBPB
ENCSR000BRX
r=0.34

small heat map img

GM12878
Myers
ELF1
ENCSR000BMB
r=0.34

small heat map img

GM12878
Myers
WRNIP1
ENCSR000EAA
r=0.34

small heat map img

GM12878
Myers
TCF12
ENCSR000BGZ
r=0.34

small heat map img

GM12878
Myers
STAT3
ENCSR000DZV
r=0.33

small heat map img

GM12878
Myers
EP300
ENCSR000DZG
r=0.33

small heat map img

GM12878
Myers
TCF3
ENCSR000BQT
r=0.32

small heat map img

GM12878
Myers
EP300
ENCSR000DZD
r=0.31

small heat map img

GM12878
Myers
JUND
ENCSR000DYS
r=0.31

small heat map img

GM12878
Myers
SREBF1
ENCSR000DYU
r=0.30

small heat map img

GM12878
Myers
PAX5
ENCSR000BHD
r=0.30

small heat map img

GM12878
Myers
SREBF2
ENCSR000DYT
r=0.29

small heat map img

GM12878
Myers
BRCA1
ENCSR000DZS
r=0.29

small heat map img

GM12878
Myers
BHLHE40
ENCSR000DZJ
r=0.29

small heat map img

GM12878
Myers
YY1
ENCSR000BNP
r=0.29

small heat map img

GM12878
Myers
E2F4
ENCSR000DYY
r=0.27

small heat map img

GM12878
Myers
MYC
ENCSR000DKU
r=0.26

small heat map img

GM12878
Myers
ETS1
ENCSR000BKA
r=0.26

small heat map img

GM12878
Myers
IRF3
ENCSR000DZX
r=0.26

small heat map img

GM12878
Myers
PBX3
ENCSR000BGR
r=0.24

small heat map img

GM12878
Myers
CREB1
ENCSR000BUF
r=0.24

small heat map img

GM12878
Myers
RAD21
ENCSR000EAC
r=0.24

small heat map img

GM12878
Myers
USF2
ENCSR000DZU
r=0.23

small heat map img

GM12878
Myers
EGR1
ENCSR000BMQ
r=0.21

small heat map img

GM12878
Myers
NRF1
ENCSR000DZO
r=0.21

small heat map img

GM12878
Myers
ZNF384
ENCSR000DYP
r=0.21

small heat map img

GM12878
Myers
MEF2A
ENCSR000BKB
r=0.21

small heat map img

GM12878
Myers
RFX5
ENCSR000DZW
r=0.20

small heat map img

GM12878
Myers
SUPT20H
ENCSR000DNP
r=0.20

small heat map img

GM12878
Myers
PAX5
ENCSR000BHJ
r=0.20

small heat map img

GM12878
Myers
IKZF1
ENCSR000EUJ
r=0.20

small heat map img

GM12878
Myers
EGR1
ENCSR000BRG
r=0.19

small heat map img

GM12878
Myers
BCL11A
ENCSR000BHA
r=0.18

small heat map img

GM12878
Myers
NFE2
ENCSR000DZY
r=0.18

small heat map img

GM12878
Myers
EP300
ENCSR000BHB
r=0.18

small heat map img

GM12878
Myers
NFYA
ENCSR000DNN
r=0.17

small heat map img

GM12878
Myers
EBF1
ENCSR000DZQ
r=0.17

small heat map img

GM12878
Myers
SP1
ENCSR000BHK
r=0.17

small heat map img

GM12878
Myers
SRF
ENCSR000BMI
r=0.17

small heat map img

GM12878
Myers
RXRA
ENCSR000BJD
r=0.17

small heat map img

GM12878
Myers
ZBTB33
ENCSR000BHC
r=0.16

small heat map img

GM12878
Myers
GABPA
ENCSR000BGC
r=0.15

small heat map img

GM12878
Myers
REST
ENCSR000BGF
r=0.15

small heat map img

GM12878
Myers
SIX5
ENCSR000BJE
r=0.14

small heat map img

GM12878
Myers
YY1
ENCSR000EUM
r=0.14

small heat map img

GM12878
Myers
IRF4
ENCSR000BGY
r=0.14

small heat map img

GM12878
Myers
ZNF143
ENCSR000DZL
r=0.14

small heat map img

GM12878
Myers
NFYB
ENCSR000DNM
r=0.14

small heat map img

GM12878
Myers
EZH2
ENCSR000ARD
r=0.14

small heat map img

GM12878
Myers
FOS
ENCSR000EYZ
r=0.14

small heat map img

GM12878
Myers
JUND
ENCSR000EYV
r=0.14

small heat map img

GM12878
Myers
EBF1
ENCSR000BGU
r=0.12

small heat map img

GM12878
Myers
MEF2C
ENCSR000BNG
r=0.12

small heat map img

GM12878
Myers
NR2C2
ENCSR000EUL
r=0.12

small heat map img

GM12878
Myers
REST
ENCSR000BQS
r=0.12

small heat map img

GM12878
Myers
POLR3G
ENCSR000EYU
r=0.11

small heat map img

GM12878
Myers
CTCF
ENCSR000DZN
r=0.11

small heat map img

GM12878
Myers
SPI1
ENCSR000BGQ
r=0.11

small heat map img

GM12878
Myers
SRF
ENCSR000BGE
r=0.11

small heat map img

GM12878
Myers
ZEB1
ENCSR000BND
r=0.10

small heat map img

GM12878
Myers
CTCF
ENCSR000AKB
r=0.10

small heat map img

GM12878
Myers
CTCF
ENCSR000DKV
r=0.10

small heat map img

GM12878
Myers
ZZZ3
ENCSR000DNQ
r=0.09

small heat map img

GM12878
Myers
USF1
ENCSR000BGI
r=0.08

small heat map img

GM12878
Myers
BATF
ENCSR000BGT
r=0.08

small heat map img

GM12878
Myers
ATF3
ENCSR000BJY
r=0.07

small heat map img

GM12878
Myers
CTCF
ENCSR000DRZ
r=0.06

small heat map img

GM12878
Myers
RAD21
ENCSR000BMY
r=0.05

small heat map img

GM12878
Myers
ZNF274
ENCSR000EUK
r=-0.07

small heat map img
0 (download )

K562 - Myers - ENCSR000FCD

K562
Myers
POLR2A
ENCSR000BMR
r=0.78

small heat map img

K562
Myers
POLR2A
ENCSR000FAJ
r=0.68

small heat map img

K562
Myers
POLR2A
ENCSR000EHP
r=0.67

small heat map img

K562
Myers
POLR2A
ENCSR000FAW
r=0.67

small heat map img

K562
Myers
POLR2A
ENCSR000FAY
r=0.65

small heat map img

K562
Myers
POLR2A
ENCSR000FAX
r=0.65

small heat map img

K562
Myers
POLR2A
ENCSR000DLY
r=0.63

small heat map img

K562
Myers
KDM5B
ENCSR000AQA
r=0.55

small heat map img

K562
Myers
ZMIZ1
ENCSR000EFQ
r=0.49

small heat map img

K562
Myers
TAF1
ENCSR000BKS
r=0.49

small heat map img

K562
Myers
TBP
ENCSR000EHA
r=0.45

small heat map img

K562
Myers
GTF2B
ENCSR000DOE
r=0.44

small heat map img

K562
Myers
IRF1
ENCSR000EGK
r=0.43

small heat map img

K562
Myers
PML
ENCSR000BQY
r=0.42

small heat map img

K562
Myers
IRF1
ENCSR000EGL
r=0.40

small heat map img

K562
Myers
CCNT2
ENCSR000DOA
r=0.40

small heat map img

K562
Myers
TBL1XR1
ENCSR000EGA
r=0.40

small heat map img

K562
Myers
PHF8
ENCSR000AQH
r=0.39

small heat map img

K562
Myers
HMGN3
ENCSR000DOB
r=0.39

small heat map img

K562
Myers
CEBPD
ENCSR000BVY
r=0.38

small heat map img

K562
Myers
TBL1XR1
ENCSR000EGB
r=0.37

small heat map img

K562
Myers
MYC
ENCSR000EGS
r=0.37

small heat map img

K562
Myers
MYC
ENCSR000EGJ
r=0.37

small heat map img

K562
Myers
CHD7
ENCSR000AVD
r=0.36

small heat map img

K562
Myers
MYC
ENCSR000FAG
r=0.36

small heat map img

K562
Myers
ELK1
ENCSR000EFU
r=0.35

small heat map img

K562
Myers
E2F4
ENCSR000EWL
r=0.35

small heat map img

K562
Myers
MXI1
ENCSR000EGZ
r=0.35

small heat map img

K562
Myers
MYC
ENCSR000EZU
r=0.35

small heat map img

K562
Myers
TAF7
ENCSR000BNM
r=0.35

small heat map img

K562
Myers
MYC
ENCSR000DLZ
r=0.35

small heat map img

K562
Myers
MAX
ENCSR000EFV
r=0.34

small heat map img

K562
Myers
SIRT6
ENCSR000AUB
r=0.33

small heat map img

K562
Myers
MYC
ENCSR000EZV
r=0.33

small heat map img

K562
Myers
MYC
ENCSR000FAZ
r=0.33

small heat map img

K562
Myers
YY1
ENCSR000BKU
r=0.33

small heat map img

K562
Myers
SETDB1
ENCSR000AUT
r=0.33

small heat map img

K562
Myers
POLR2A
ENCSR000EHL
r=0.32

small heat map img

K562
Myers
TAL1
ENCSR000EHB
r=0.32

small heat map img

K562
Myers
TRIM28
ENCSR000BRW
r=0.32

small heat map img

K562
Myers
HDAC6
ENCSR000ATJ
r=0.32

small heat map img

K562
Myers
JUN
ENCSR000EFS
r=0.32

small heat map img

K562
Myers
MAX
ENCSR000BLP
r=0.31

small heat map img

K562
Myers
RBBP5
ENCSR000AQI
r=0.31

small heat map img

K562
Myers
JUND
ENCSR000EGN
r=0.31

small heat map img

K562
Myers
GATA1
ENCSR000EFT
r=0.30

small heat map img

K562
Myers
STAT2
ENCSR000FAT
r=0.30

small heat map img

K562
Myers
JUN
ENCSR000FAH
r=0.30

small heat map img

K562
Myers
RCOR1
ENCSR000EGG
r=0.30

small heat map img

K562
Myers
JUN
ENCSR000EGH
r=0.30

small heat map img

K562
Myers
CREB1
ENCSR000BSO
r=0.29

small heat map img

K562
Myers
REST
ENCSR000BMW
r=0.29

small heat map img

K562
Myers
IRF1
ENCSR000EGT
r=0.28

small heat map img

K562
Myers
CHD1
ENCSR000AQD
r=0.28

small heat map img

K562
Myers
STAT1
ENCSR000EHJ
r=0.28

small heat map img

K562
Myers
ELF1
ENCSR000BMD
r=0.28

small heat map img

K562
Myers
SMARCA4
ENCSR000EHO
r=0.28

small heat map img

K562
Myers
E2F6
ENCSR000EWJ
r=0.27

small heat map img

K562
Myers
SMC3
ENCSR000EGW
r=0.27

small heat map img

K562
Myers
RCOR1
ENCSR000EGC
r=0.27

small heat map img

K562
Myers
EP300
ENCSR000EGE
r=0.26

small heat map img

K562
Myers
ETS1
ENCSR000BKQ
r=0.26

small heat map img

K562
Myers
CBX3
ENCSR000BRT
r=0.26

small heat map img

K562
Myers
TEAD4
ENCSR000BRK
r=0.26

small heat map img

K562
Myers
HCFC1
ENCSR000EFN
r=0.26

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K562
Myers
MAX
ENCSR000FAE
r=0.26

small heat map img

K562
Myers
SETDB1
ENCSR000EWI
r=0.25

small heat map img

K562
Myers
STAT1
ENCSR000EHK
r=0.25

small heat map img

K562
Myers
ATF1
ENCSR000DNZ
r=0.25

small heat map img

K562
Myers
YY1
ENCSR000EWF
r=0.25

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K562
Myers
SMARCB1
ENCSR000EHN
r=0.24

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K562
Myers
STAT5A
ENCSR000BRR
r=0.24

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K562
Myers
BHLHE40
ENCSR000EGV
r=0.24

small heat map img

K562
Myers
HDAC1
ENCSR000AQF
r=0.24

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K562
Myers
SAP30
ENCSR000AQJ
r=0.23

small heat map img

K562
Myers
STAT1
ENCSR000FAU
r=0.23

small heat map img

K562
Myers
KAT2B
ENCSR000ATZ
r=0.23

small heat map img

K562
Myers
EGR1
ENCSR000BNE
r=0.23

small heat map img

K562
Myers
ARID3A
ENCSR000EFY
r=0.23

small heat map img

K562
Myers
STAT1
ENCSR000FAV
r=0.22

small heat map img

K562
Myers
NR2F2
ENCSR000BRS
r=0.22

small heat map img

K562
Myers
MAFK
ENCSR000EGX
r=0.21

small heat map img

K562
Myers
STAT2
ENCSR000FBC
r=0.21

small heat map img

K562
Myers
SIN3A
ENCSR000BLR
r=0.21

small heat map img

K562
Myers
BACH1
ENCSR000EGD
r=0.20

small heat map img

K562
Myers
ZNF384
ENCSR000EFP
r=0.19

small heat map img

K562
Myers
GABPA
ENCSR000BLO
r=0.19

small heat map img

K562
Myers
JUN
ENCSR000EZX
r=0.19

small heat map img

K562
Myers
ZNF263
ENCSR000EWN
r=0.18

small heat map img

K562
Myers
HDAC2
ENCSR000AQG
r=0.18

small heat map img

K562
Myers
WHSC1
ENCSR000AVE
r=0.18

small heat map img

K562
Myers
CEBPB
ENCSR000BRQ
r=0.18

small heat map img

K562
Myers
SRF
ENCSR000BLK
r=0.18

small heat map img

K562
Myers
YY1
ENCSR000BMH
r=0.18

small heat map img

K562
Myers
EP300
ENCSR000EGY
r=0.17

small heat map img

K562
Myers
USF2
ENCSR000EHG
r=0.17

small heat map img

K562
Myers
UBTF
ENCSR000EFZ
r=0.17

small heat map img

K562
Myers
ATF3
ENCSR000BNU
r=0.17

small heat map img

K562
Myers
CUX1
ENCSR000EFO
r=0.17

small heat map img

K562
Myers
GATA2
ENCSR000EWG
r=0.17

small heat map img

K562
Myers
JUN
ENCSR000EZT
r=0.17

small heat map img

K562
Myers
NRF1
ENCSR000EHH
r=0.17

small heat map img

K562
Myers
ATF3
ENCSR000DOG
r=0.17

small heat map img

K562
Myers
ZBTB33
ENCSR000BKF
r=0.17

small heat map img

K562
Myers
E2F6
ENCSR000BLI
r=0.16

small heat map img

K562
Myers
NFYA
ENCSR000EGR
r=0.16

small heat map img

K562
Myers
MEF2A
ENCSR000BNV
r=0.16

small heat map img

K562
Myers
NFE2
ENCSR000FAF
r=0.16

small heat map img

K562
Myers
ZNF143
ENCSR000EGP
r=0.15

small heat map img

K562
Myers
MAFF
ENCSR000EGI
r=0.15

small heat map img

K562
Myers
RFX5
ENCSR000EGO
r=0.15

small heat map img

K562
Myers
NCOR1
ENCSR000ATY
r=0.15

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K562
Myers
GATA1
ENCSR000EWM
r=0.15

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K562
Myers
GATA2
ENCSR000BKM
r=0.15

small heat map img

K562
Myers
GTF3C2
ENCSR000DOD
r=0.15

small heat map img

K562
Myers
ZNF274
ENCSR000EVX
r=0.14

small heat map img

K562
Myers
HDAC2
ENCSR000BMG
r=0.14

small heat map img

K562
Myers
USF1
ENCSR000BKT
r=0.14

small heat map img

K562
Myers
ZBTB7A
ENCSR000BME
r=0.14

small heat map img

K562
Myers
IRF1
ENCSR000EGU
r=0.14

small heat map img

K562
Myers
UBTF
ENCSR000EFW
r=0.14

small heat map img

K562
Myers
NFYB
ENCSR000EGQ
r=0.13

small heat map img

K562
Myers
CREBBP
ENCSR000ATT
r=0.13

small heat map img

K562
Myers
EP300
ENCSR000AQB
r=0.13

small heat map img

K562
Myers
CBX3
ENCSR000ATV
r=0.13

small heat map img

K562
Myers
CTCF
ENCSR000EGM
r=0.13

small heat map img

K562
Myers
JUN
ENCSR000EZW
r=0.13

small heat map img

K562
Myers
CTCFL
ENCSR000BNK
r=0.12

small heat map img

K562
Myers
CEBPB
ENCSR000EHE
r=0.12

small heat map img

K562
Myers
RNF2
ENCSR000AUA
r=0.12

small heat map img

K562
Myers
FOS
ENCSR000FAI
r=0.12

small heat map img

K562
Myers
SPI1
ENCSR000BGW
r=0.12

small heat map img

K562
Myers
SIRT6
ENCSR000DOH
r=0.11

small heat map img

K562
Myers
SUZ12
ENCSR000AUC
r=0.11

small heat map img

K562
Myers
THAP1
ENCSR000BNN
r=0.11

small heat map img

K562
Myers
XRCC4
ENCSR000FAC
r=0.11

small heat map img

K562
Myers
TRIM28
ENCSR000EVY
r=0.11

small heat map img

K562
Myers
BRF2
ENCSR000DOC
r=0.10

small heat map img

K562
Myers
RAD21
ENCSR000FAD
r=0.10

small heat map img

K562
Myers
SP2
ENCSR000BNL
r=0.10

small heat map img

K562
Myers
FOSL1
ENCSR000BMV
r=0.10

small heat map img

K562
Myers
REST
ENCSR000ATM
r=0.10

small heat map img

K562
Myers
CTCF
ENCSR000BPJ
r=0.09

small heat map img

K562
Myers
CTCF
ENCSR000AKO
r=0.09

small heat map img

K562
Myers
SP1
ENCSR000BKO
r=0.09

small heat map img

K562
Myers
CTCF
ENCSR000DMA
r=0.09

small heat map img

K562
Myers
CTCF
ENCSR000DWE
r=0.09

small heat map img

K562
Myers
KDM1A
ENCSR000ATX
r=0.08

small heat map img

K562
Myers
CHD4
ENCSR000ATL
r=0.06

small heat map img

K562
Myers
SIX5
ENCSR000BGX
r=0.06

small heat map img

K562
Myers
RAD21
ENCSR000BKV
r=0.06

small heat map img

K562
Myers
EZH2
ENCSR000AQE
r=0.05

small heat map img

K562
Myers
CBX2
ENCSR000ATU
r=0.04

small heat map img

K562
Myers
NR2C2
ENCSR000EWH
r=0.03

small heat map img

K562
Myers
SIX5
ENCSR000BNW
r=0.03

small heat map img

K562
Myers
SETDB1
ENCSR000EWD
r=0.03

small heat map img

K562
Myers
BRF1
ENCSR000DOJ
r=0.01

small heat map img

K562
Myers
POLR3A
ENCSR000DOI
r=0.01

small heat map img

K562
Myers
POLR3G
ENCSR000EHQ
r=0.01

small heat map img

K562
Myers
BDP1
ENCSR000DOK
r=-0.00

small heat map img

K562
Myers
CBX8
ENCSR000ATW
r=-0.01

small heat map img

K562
Myers
ZNF274
ENCSR000EWE
r=-0.10

small heat map img
0 (download )

Notes

Peaks (left to right in the heatmap) are sorted by the descending order of [-log10(q-value), -log10(p-value), TF ChIP-seq signal].

legend

Average Profiles of Nucleosomes around the Summit of ChIP-seq Peaks

GM12878 - Myers - ENCSR251OVJ

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K562 - Myers - ENCSR000FCD

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Notes

Average nucleosome occupancy profiles in GM12878 and K562 cells are shown for the [-2 kb, +2 kb] window centered on the summits of the TF ChIP-seq peaks, separately for peaks that are proximal to an annotated transcription start site (red lines) and for peaks that are distal to all annotated transcription start sites (blue lines), as defined in the Histone section.

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