ELK1 - Factorbook

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. RefSeq, Mar 2012

ETS domain-containing protein Elk-1 is a protein that in humans is encoded by the ELK1 gene. Elk-1 functions as a transcription activator.wikipedia

ELK1
PDB 1DUX
PDB	1DUX
ENCODE	experiments
Ensemble	search
Entrez	2002
GO	search
Gene Card	search
HGNC	search
RefSeq	search
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Wikipedia	ELK1

Average Profiles of Modified Histones around the Summit of ChIP-seq Peaks

GM12878 - Snyder - ENCSR000DZB

HeLa-S3 - Snyder - ENCSR000ECI

K562 - Snyder - ENCSR000EFU

Legend

Proximal:

H2AFZ
H3K27ac
H3K27me3
H3K36me3
H3K4me1
H3K4me2
H3K4me3
H3K79me2
H3K9ac
H3K9me1
H3K9me3
H4K20me1

Distal:

H2AFZ
H3K27ac
H3K27me3
H3K36me3
H3K4me1
H3K4me2
H3K4me3
H3K79me2
H3K9ac
H3K9me1
H3K9me3
H4K20me1

Notes

Average histone modification profiles are shown for the [-2 kb, +2 kb] window around the summits of TF ChIP-seq peaks. Profile are shown separately for peaks that are proximal ([-1 kb, +1 kb]; ending in '-p') to an annotated transcript start site (TSS) and for peaks that are distal (>1 kb; ending in '-d') to all annotated TSS. TSS-proximal profiles are arranged such that the nearest transcript proceeds towards the right.

Motifs Enriched in the Top 500 ChIP-seq Peaks

GM12878 - Snyder - ENCSR000DZB

1. 475 / 500 7.4e-639 GACCGGAAGTG		p-value: 0.00 pct_center: 0.57 pct_ratio: 2.21
2. 100 / 500 2.2e-60 CCATATAAGGA		p-value: 0.00 pct_center: 0.07 pct_ratio: 0.83
3. 20 / 500 1.4e-30 GCCTTCTGGGAGTTGTAGTTC		p-value: 0.00 pct_center: 0.18 pct_ratio: 0.83
4. 140 / 500 6.0e-27 CGGAAGTG		p-value: 0.00 pct_center: 0.42 pct_ratio: 2.86
5. 34 / 500 1.7e-14 TGTTTTTTTTTTTTT		p-value: 0.91 pct_center: 0.13 pct_ratio: 0.34

MEME output

Notes

The top 500 TF ChIP-seq peaks were used to identify enriched motifs de novo, using the MEME-ChIP suite of tools. Up to five motifs are reported (1 to 5) if they meet the criteria defined by our pipeline.

HeLa-S3 - Snyder - ENCSR000ECI

1. 475 / 500 1.3e-738 ACCGGAAGTGG		p-value: 0.00 pct_center: 0.63 pct_ratio: 2.49
2. 155 / 500 3.1e-56 CGGAAGTG		p-value: 0.00 pct_center: 0.47 pct_ratio: 3.15
3. 64 / 500 9.4e-48 CCTTATATGGG		p-value: 0.00 pct_center: 0.05 pct_ratio: 0.61
4. 15 / 500 9.4e-17 GCCTGCTGGGAGTTGTAGTTC		p-value: 0.00 pct_center: 0.21 pct_ratio: 0.75
5. 20 / 500 0.0019 TCAAGATGGCGGC		p-value: 0.00 pct_center: 0.15 pct_ratio: 0.74

MEME output

Notes

K562 - Snyder - ENCSR000EFU

1. 464 / 500 6.5e-709 GACCGGAAGTGGC		p-value: 0.00 pct_center: 0.68 pct_ratio: 2.39
2. 33 / 500 1.3e-231 TATATGGTCTAAAAAGGGGAGGAACCCT		p-value: 0.00 pct_center: 0.07 pct_ratio: 0.60
3. 28 / 500 8.9e-201 GTTGCCATGGCATTTGTAAACTGTCATGG		p-value: 0.00 pct_center: 0.05 pct_ratio: 0.81
4. 64 / 500 2.3e-49 ACCATATAAGG		p-value: 0.00 pct_center: 0.06 pct_ratio: 0.88
5. 26 / 500 3.9e-46 CAGTTCCGGGAATTG		p-value: 0.00 pct_center: 0.09 pct_ratio: 0.83

MEME output

Notes

Binding of other histone marks at ELK1 peaks

GM12878 - Snyder - ENCSR000DZB

GM12878 Snyder ELK1 ENCSR000DZB r=1.00
GM12878 Snyder H2AFZ ENCSR000AOV r=0.55
GM12878 Snyder H3K9ac ENCSR000AKH r=0.50
GM12878 Snyder H3K4me3 ENCSR000DRY r=0.47
GM12878 Snyder H3K4me3 ENCSR000AKA r=0.46
GM12878 Snyder H3K27ac ENCSR000AKC r=0.43
GM12878 Snyder H3K4me2 ENCSR000AKG r=0.36
GM12878 Snyder H3K79me2 ENCSR000AOW r=0.21
GM12878 Snyder H3K4me1 ENCSR000AKF r=0.06
GM12878 Snyder H3K9me3 ENCSR000AOX r=0.04
GM12878 Snyder H3K27me3 ENCSR000AKD r=-0.05
GM12878 Snyder H4K20me1 ENCSR000AKI r=-0.05
GM12878 Snyder H3K27me3 ENCSR000DRX r=-0.06
GM12878 Snyder H3K36me3 ENCSR000DRW r=-0.09
GM12878 Snyder H3K36me3 ENCSR000AKE r=-0.17

5,584 peaks (download )

HeLa-S3 - Snyder - ENCSR000ECI

HeLa-S3 Snyder ELK1 ENCSR000ECI r=1.00
HeLa-S3 Snyder H3K4me3 ENCSR000AOF r=0.55
HeLa-S3 Snyder H3K9ac ENCSR000AOH r=0.55
HeLa-S3 Snyder H2AFZ ENCSR000AQN r=0.55
HeLa-S3 Snyder H3K27ac ENCSR000AOC r=0.53
HeLa-S3 Snyder H3K4me3 ENCSR000DUA r=0.53
HeLa-S3 Snyder H3K4me2 ENCSR000AOE r=0.41
HeLa-S3 Snyder H3K4me1 ENCSR000APW r=0.13
HeLa-S3 Snyder H3K79me2 ENCSR000AOG r=0.10
HeLa-S3 Snyder H3K27me3 ENCSR000DTY r=0.08
HeLa-S3 Snyder H3K9me3 ENCSR000AQO r=-0.00
HeLa-S3 Snyder H3K27me3 ENCSR000APB r=-0.03
HeLa-S3 Snyder H4K20me1 ENCSR000AOI r=-0.06
HeLa-S3 Snyder H3K36me3 ENCSR000DTZ r=-0.06
HeLa-S3 Snyder H3K36me3 ENCSR000AOD r=-0.18

4,809 peaks (download )

K562 - Snyder - ENCSR000EFU

K562 Snyder ELK1 ENCSR000EFU r=1.00
K562 Snyder H2AFZ ENCSR000APC r=0.49
K562 Snyder H3K9ac ENCSR000AKV r=0.48
K562 Snyder H3K4me3 ENCSR000AKU r=0.48
K562 Snyder H3K9ac ENCSR000EVZ r=0.47
K562 Snyder H3K4me2 ENCSR000AKT r=0.47
K562 Snyder H3K27ac ENCSR000AKP r=0.47
K562 Snyder H3K4me3 ENCSR000DWD r=0.46
K562 Snyder H3K4me3 ENCSR000EWA r=0.45
K562 Snyder H3K4me1 ENCSR000EWC r=0.19
K562 Snyder H3K79me2 ENCSR000APD r=0.17
K562 Snyder H4K20me1 ENCSR000AKX r=0.14
K562 Snyder H3K9me3 ENCSR000APE r=0.13
K562 Snyder H3K9me1 ENCSR000AKW r=0.10
K562 Snyder H3K27me3 ENCSR000AKQ r=0.10
K562 Snyder H3K4me1 ENCSR000AKS r=0.09
K562 Snyder H3K27me3 ENCSR000DWC r=0.07
K562 Snyder H3K27me3 ENCSR000EWB r=0.03
K562 Snyder H3K36me3 ENCSR000AKR r=-0.03
K562 Snyder H3K36me3 ENCSR000DWB r=-0.04

2,961 peaks (download )

Notes

ChIP-seq peaks (left to right in the heatmap) for the current TF are sorted by descending TF ChIP-seq signal. The ChIP-seq signals of histone modifications are plotted for the genomic regions that correspond to the peaks of the current TF in the same order. The Pearson correlation coefficient (r) of the histone modification ChIP-seq signal with the TF ChIP-seq signal is shown.

Binding of other TFs at ELK1 peaks

GM12878 - Snyder - ENCSR000DZB

GM12878 Snyder ELK1 ENCSR000DZB r=1.00
GM12878 Snyder ELF1 ENCSR000BMB r=0.72
GM12878 Snyder STAT1 ENCSR000DZM r=0.71
GM12878 Snyder TBL1XR1 ENCSR000DYZ r=0.70
GM12878 Snyder MAX ENCSR000DZF r=0.67
GM12878 Snyder RCOR1 ENCSR000DZC r=0.67
GM12878 Snyder MXI1 ENCSR000DZI r=0.67
GM12878 Snyder SIN3A ENCSR000DYX r=0.64
GM12878 Snyder ESRRA ENCSR000DYQ r=0.63
GM12878 Snyder SREBF1 ENCSR000DYU r=0.61
GM12878 Snyder SREBF2 ENCSR000DYT r=0.60
GM12878 Snyder ETS1 ENCSR000BKA r=0.58
GM12878 Snyder POLR2A ENCSR000DKT r=0.58
GM12878 Snyder CREB1 ENCSR000BUF r=0.57
GM12878 Snyder GABPA ENCSR000BGC r=0.57
GM12878 Snyder RUNX3 ENCSR000BRI r=0.57
GM12878 Snyder RELA ENCSR000EAG r=0.56
GM12878 Snyder EP300 ENCSR000DZG r=0.55
GM12878 Snyder JUND ENCSR000DYS r=0.54
GM12878 Snyder POLR2A ENCSR000EAD r=0.53
GM12878 Snyder BHLHE40 ENCSR000DZJ r=0.53
GM12878 Snyder PML ENCSR000BQM r=0.53
GM12878 Snyder EP300 ENCSR000DZD r=0.53
GM12878 Snyder MAFK ENCSR000DYV r=0.52
GM12878 Snyder STAT3 ENCSR000DZV r=0.52
GM12878 Snyder RFX5 ENCSR000DZW r=0.51
GM12878 Snyder TBP ENCSR000DZZ r=0.51
GM12878 Snyder POLR2A ENCSR000EYW r=0.50
GM12878 Snyder PAX5 ENCSR000BHD r=0.50
GM12878 Snyder CUX1 ENCSR000DYR r=0.50
GM12878 Snyder E2F4 ENCSR000DYY r=0.50
GM12878 Snyder SRF ENCSR000BMI r=0.49
GM12878 Snyder BRCA1 ENCSR000DZS r=0.48
GM12878 Snyder POLR2A ENCSR000BGD r=0.48
GM12878 Snyder IRF3 ENCSR000DZX r=0.47
GM12878 Snyder MYC ENCSR000DKU r=0.47
GM12878 Snyder SIX5 ENCSR000BJE r=0.47
GM12878 Snyder NRF1 ENCSR000DZO r=0.47
GM12878 Snyder YY1 ENCSR000BNP r=0.47
GM12878 Snyder WRNIP1 ENCSR000EAA r=0.46
GM12878 Snyder SMC3 ENCSR000DZP r=0.45
GM12878 Snyder ATF2 ENCSR000BQK r=0.45
GM12878 Snyder TCF12 ENCSR000BGZ r=0.44
GM12878 Snyder CHD1 ENCSR000DZE r=0.43
GM12878 Snyder ZNF143 ENCSR000DZL r=0.43
GM12878 Snyder POU2F2 ENCSR000BGP r=0.43
GM12878 Snyder FOXM1 ENCSR000BRU r=0.43
GM12878 Snyder SP1 ENCSR000BHK r=0.42
GM12878 Snyder SRF ENCSR000BGE r=0.40
GM12878 Snyder USF2 ENCSR000DZU r=0.40
GM12878 Snyder KAT2A ENCSR000DNO r=0.40
GM12878 Snyder TAF1 ENCSR000BGS r=0.39
GM12878 Snyder NFIC ENCSR000BRN r=0.39
GM12878 Snyder EGR1 ENCSR000BRG r=0.38
GM12878 Snyder TCF3 ENCSR000BQT r=0.37
GM12878 Snyder NFE2 ENCSR000DZY r=0.37
GM12878 Snyder BCL3 ENCSR000BNQ r=0.37
GM12878 Snyder ZNF384 ENCSR000DYP r=0.37
GM12878 Snyder EGR1 ENCSR000BMQ r=0.37
GM12878 Snyder CEBPB ENCSR000BRX r=0.36
GM12878 Snyder FOS ENCSR000EYZ r=0.36
GM12878 Snyder RAD21 ENCSR000EAC r=0.35
GM12878 Snyder MEF2A ENCSR000BKB r=0.32
GM12878 Snyder NFYA ENCSR000DNN r=0.31
GM12878 Snyder STAT5A ENCSR000BQZ r=0.31
GM12878 Snyder SUPT20H ENCSR000DNP r=0.30
GM12878 Snyder CTCF ENCSR000DZN r=0.30
GM12878 Snyder NFATC1 ENCSR000BQL r=0.30
GM12878 Snyder NFYB ENCSR000DNM r=0.29
GM12878 Snyder IRF4 ENCSR000BGY r=0.28
GM12878 Snyder EBF1 ENCSR000DZQ r=0.28
GM12878 Snyder PAX5 ENCSR000BHJ r=0.28
GM12878 Snyder NR2C2 ENCSR000EUL r=0.25
GM12878 Snyder EP300 ENCSR000BHB r=0.25
GM12878 Snyder CTCF ENCSR000DKV r=0.25
GM12878 Snyder USF1 ENCSR000BGI r=0.24
GM12878 Snyder MTA3 ENCSR000BRH r=0.24
GM12878 Snyder CTCF ENCSR000AKB r=0.24
GM12878 Snyder RXRA ENCSR000BJD r=0.23
GM12878 Snyder IKZF1 ENCSR000EUJ r=0.23
GM12878 Snyder SPI1 ENCSR000BGQ r=0.22
GM12878 Snyder CTCF ENCSR000DRZ r=0.22
GM12878 Snyder PBX3 ENCSR000BGR r=0.21
GM12878 Snyder ZBTB33 ENCSR000BHC r=0.21
GM12878 Snyder EBF1 ENCSR000BGU r=0.20
GM12878 Snyder ATF3 ENCSR000BJY r=0.19
GM12878 Snyder BCL11A ENCSR000BHA r=0.19
GM12878 Snyder POLR3G ENCSR000EYU r=0.19
GM12878 Snyder YY1 ENCSR000EUM r=0.19
GM12878 Snyder JUND ENCSR000EYV r=0.17
GM12878 Snyder MEF2C ENCSR000BNG r=0.16
GM12878 Snyder ZZZ3 ENCSR000DNQ r=0.16
GM12878 Snyder ZEB1 ENCSR000BND r=0.16
GM12878 Snyder RAD21 ENCSR000BMY r=0.16
GM12878 Snyder EZH2 ENCSR000ARD r=0.15
GM12878 Snyder REST ENCSR000BGF r=0.13
GM12878 Snyder BATF ENCSR000BGT r=0.12
GM12878 Snyder REST ENCSR000BQS r=0.11
GM12878 Snyder ZNF274 ENCSR000EUK r=-0.14

5,584 peaks (download )

HeLa-S3 - Snyder - ENCSR000ECI

HeLa-S3 Snyder ELK1 ENCSR000ECI r=1.00
HeLa-S3 Snyder ELK4 ENCSR000EVI r=0.83
HeLa-S3 Snyder HCFC1 ENCSR000ECH r=0.78
HeLa-S3 Snyder RCOR1 ENCSR000ECM r=0.73
HeLa-S3 Snyder MAX ENCSR000ECN r=0.72
HeLa-S3 Snyder MXI1 ENCSR000ECU r=0.70
HeLa-S3 Snyder ZKSCAN1 ENCSR000ECJ r=0.68
HeLa-S3 Snyder MYC ENCSR000EZD r=0.68
HeLa-S3 Snyder MAFK ENCSR000ECK r=0.68
HeLa-S3 Snyder MAX ENCSR000EZF r=0.66
HeLa-S3 Snyder BRCA1 ENCSR000EDB r=0.63
HeLa-S3 Snyder POLR2A ENCSR000DLM r=0.61
HeLa-S3 Snyder STAT1 ENCSR000EZK r=0.58
HeLa-S3 Snyder SMC3 ENCSR000ECS r=0.58
HeLa-S3 Snyder GABPA ENCSR000BHS r=0.57
HeLa-S3 Snyder RFX5 ENCSR000ECX r=0.56
HeLa-S3 Snyder MYC ENCSR000DLN r=0.54
HeLa-S3 Snyder E2F4 ENCSR000EVL r=0.53
HeLa-S3 Snyder POLR2A ENCSR000EZL r=0.53
HeLa-S3 Snyder JUND ENCSR000EDH r=0.53
HeLa-S3 Snyder ZNF143 ENCSR000ECO r=0.51
HeLa-S3 Snyder TCF7L2 ENCSR000EVE r=0.50
HeLa-S3 Snyder TBP ENCSR000EDD r=0.49
HeLa-S3 Snyder FOS ENCSR000EZE r=0.49
HeLa-S3 Snyder POLR2A ENCSR000BGO r=0.48
HeLa-S3 Snyder E2F6 ENCSR000EVK r=0.47
HeLa-S3 Snyder E2F1 ENCSR000EVJ r=0.46
HeLa-S3 Snyder KAT2A ENCSR000ECR r=0.46
HeLa-S3 Snyder STAT3 ENCSR000EDC r=0.46
HeLa-S3 Snyder CEBPB ENCSR000EDA r=0.45
HeLa-S3 Snyder JUN ENCSR000EDG r=0.45
HeLa-S3 Snyder PRDM1 ENCSR000ECY r=0.44
HeLa-S3 Snyder SMARCB1 ENCSR000EDK r=0.44
HeLa-S3 Snyder NR2C2 ENCSR000EVN r=0.43
HeLa-S3 Snyder NRF1 ENCSR000EDJ r=0.42
HeLa-S3 Snyder NFYA ENCSR000DNS r=0.42
HeLa-S3 Snyder USF2 ENCSR000ECW r=0.41
HeLa-S3 Snyder IRF3 ENCSR000EDF r=0.39
HeLa-S3 Snyder EP300 ENCSR000ECV r=0.38
HeLa-S3 Snyder SUPT20H ENCSR000ECQ r=0.38
HeLa-S3 Snyder SMARCC1 ENCSR000EDM r=0.37
HeLa-S3 Snyder SMARCC2 ENCSR000EDL r=0.37
HeLa-S3 Snyder TAF1 ENCSR000BHT r=0.36
HeLa-S3 Snyder TCF7L2 ENCSR000EVF r=0.36
HeLa-S3 Snyder RAD21 ENCSR000EDE r=0.36
HeLa-S3 Snyder NFYB ENCSR000DNR r=0.32
HeLa-S3 Snyder CTCF ENCSR000DLO r=0.28
HeLa-S3 Snyder CTCF ENCSR000DUB r=0.27
HeLa-S3 Snyder SMARCA4 ENCSR000EZC r=0.25
HeLa-S3 Snyder CTCF ENCSR000AOA r=0.24
HeLa-S3 Snyder ZNF274 ENCSR000EVG r=0.20
HeLa-S3 Snyder EZH2 ENCSR000ATC r=0.16
HeLa-S3 Snyder ZZZ3 ENCSR000DNT r=0.12
HeLa-S3 Snyder REST ENCSR000BMN r=0.10
HeLa-S3 Snyder BRF2 ENCSR000DNV r=0.08
HeLa-S3 Snyder POLR3A ENCSR000DNU r=0.05
HeLa-S3 Snyder GTF3C2 ENCSR000DNY r=0.05
HeLa-S3 Snyder BDP1 ENCSR000DNX r=0.02
HeLa-S3 Snyder BRF1 ENCSR000DNW r=-0.10

4,809 peaks (download )

K562 - Snyder - ENCSR000EFU

K562 Snyder ELK1 ENCSR000EFU r=1.00
K562 Snyder IRF1 ENCSR000EGL r=0.67
K562 Snyder IRF1 ENCSR000EGK r=0.67
K562 Snyder JUN ENCSR000EGH r=0.66
K562 Snyder TBL1XR1 ENCSR000EGB r=0.66
K562 Snyder JUND ENCSR000EGN r=0.64
K562 Snyder JUN ENCSR000EFS r=0.63
K562 Snyder STAT2 ENCSR000FAT r=0.63
K562 Snyder TBL1XR1 ENCSR000EGA r=0.63
K562 Snyder STAT1 ENCSR000EHJ r=0.62
K562 Snyder MXI1 ENCSR000EGZ r=0.62
K562 Snyder ZMIZ1 ENCSR000EFQ r=0.61
K562 Snyder EP300 ENCSR000EGE r=0.61
K562 Snyder MYC ENCSR000EGS r=0.60
K562 Snyder IRF1 ENCSR000EGT r=0.60
K562 Snyder MYC ENCSR000FAZ r=0.59
K562 Snyder RCOR1 ENCSR000EGG r=0.59
K562 Snyder MYC ENCSR000EZV r=0.59
K562 Snyder JUN ENCSR000FAH r=0.59
K562 Snyder ELF1 ENCSR000BMD r=0.58
K562 Snyder MYC ENCSR000EZU r=0.58
K562 Snyder HCFC1 ENCSR000EFN r=0.58
K562 Snyder STAT1 ENCSR000EHK r=0.57
K562 Snyder MYC ENCSR000EGJ r=0.57
K562 Snyder ATF1 ENCSR000DNZ r=0.57
K562 Snyder MYC ENCSR000FAG r=0.56
K562 Snyder GABPA ENCSR000BLO r=0.56
K562 Snyder STAT1 ENCSR000FAV r=0.56
K562 Snyder MAFK ENCSR000EGX r=0.56
K562 Snyder MAX ENCSR000EFV r=0.56
K562 Snyder E2F4 ENCSR000EWL r=0.56
K562 Snyder STAT1 ENCSR000FAU r=0.56
K562 Snyder RCOR1 ENCSR000EGC r=0.55
K562 Snyder GATA1 ENCSR000EFT r=0.55
K562 Snyder ARID3A ENCSR000EFY r=0.55
K562 Snyder STAT2 ENCSR000FBC r=0.55
K562 Snyder TRIM28 ENCSR000BRW r=0.54
K562 Snyder POLR2A ENCSR000FAY r=0.54
K562 Snyder SETDB1 ENCSR000AUT r=0.54
K562 Snyder POLR2A ENCSR000DLY r=0.54
K562 Snyder SRF ENCSR000BLK r=0.54
K562 Snyder POLR2A ENCSR000FAW r=0.53
K562 Snyder POLR2A ENCSR000FAX r=0.53
K562 Snyder HMGN3 ENCSR000DOB r=0.52
K562 Snyder POLR2A ENCSR000EHP r=0.51
K562 Snyder JUN ENCSR000EZX r=0.51
K562 Snyder CBX3 ENCSR000BRT r=0.51
K562 Snyder CCNT2 ENCSR000DOA r=0.51
K562 Snyder KDM5B ENCSR000AQA r=0.51
K562 Snyder POLR2A ENCSR000FAJ r=0.51
K562 Snyder JUN ENCSR000EZT r=0.50
K562 Snyder STAT5A ENCSR000BRR r=0.50
K562 Snyder BHLHE40 ENCSR000EGV r=0.50
K562 Snyder CREB1 ENCSR000BSO r=0.50
K562 Snyder MAX ENCSR000FAE r=0.50
K562 Snyder MYC ENCSR000DLZ r=0.50
K562 Snyder CUX1 ENCSR000EFO r=0.49
K562 Snyder EP300 ENCSR000EGY r=0.49
K562 Snyder SMC3 ENCSR000EGW r=0.49
K562 Snyder ETS1 ENCSR000BKQ r=0.48
K562 Snyder POLR2A ENCSR000BMR r=0.48
K562 Snyder KAT2B ENCSR000ATZ r=0.47
K562 Snyder MAX ENCSR000BLP r=0.47
K562 Snyder CEBPD ENCSR000BVY r=0.47
K562 Snyder GTF2B ENCSR000DOE r=0.47
K562 Snyder TAF1 ENCSR000BKS r=0.46
K562 Snyder JUN ENCSR000EZW r=0.46
K562 Snyder IRF1 ENCSR000EGU r=0.46
K562 Snyder BACH1 ENCSR000EGD r=0.45
K562 Snyder SETDB1 ENCSR000EWI r=0.45
K562 Snyder CHD7 ENCSR000AVD r=0.44
K562 Snyder PML ENCSR000BQY r=0.44
K562 Snyder TEAD4 ENCSR000BRK r=0.44
K562 Snyder NR2F2 ENCSR000BRS r=0.44
K562 Snyder ZNF384 ENCSR000EFP r=0.44
K562 Snyder TBP ENCSR000EHA r=0.43
K562 Snyder RFX5 ENCSR000EGO r=0.43
K562 Snyder HDAC6 ENCSR000ATJ r=0.43
K562 Snyder YY1 ENCSR000BKU r=0.42
K562 Snyder MAFF ENCSR000EGI r=0.42
K562 Snyder ATF3 ENCSR000BNU r=0.42
K562 Snyder EP300 ENCSR000AQB r=0.41
K562 Snyder ATF3 ENCSR000DOG r=0.41
K562 Snyder RBBP5 ENCSR000AQI r=0.41
K562 Snyder ZNF143 ENCSR000EGP r=0.40
K562 Snyder CEBPB ENCSR000BRQ r=0.40
K562 Snyder E2F6 ENCSR000EWJ r=0.40
K562 Snyder POLR2A ENCSR000EHL r=0.39
K562 Snyder SIRT6 ENCSR000DOH r=0.39
K562 Snyder TAL1 ENCSR000EHB r=0.39
K562 Snyder NRF1 ENCSR000EHH r=0.38
K562 Snyder EGR1 ENCSR000BNE r=0.38
K562 Snyder NFE2 ENCSR000FAF r=0.38
K562 Snyder TRIM28 ENCSR000EVY r=0.37
K562 Snyder HDAC1 ENCSR000AQF r=0.36
K562 Snyder REST ENCSR000BMW r=0.35
K562 Snyder SMARCA4 ENCSR000EHO r=0.35
K562 Snyder NFYA ENCSR000EGR r=0.35
K562 Snyder SAP30 ENCSR000AQJ r=0.35
K562 Snyder USF1 ENCSR000BKT r=0.35
K562 Snyder CTCF ENCSR000EGM r=0.35
K562 Snyder SMARCB1 ENCSR000EHN r=0.34
K562 Snyder FOS ENCSR000FAI r=0.34
K562 Snyder SIN3A ENCSR000BLR r=0.34
K562 Snyder HDAC2 ENCSR000AQG r=0.34
K562 Snyder WHSC1 ENCSR000AVE r=0.34
K562 Snyder PHF8 ENCSR000AQH r=0.34
K562 Snyder YY1 ENCSR000EWF r=0.34
K562 Snyder SPI1 ENCSR000BGW r=0.34
K562 Snyder TAF7 ENCSR000BNM r=0.33
K562 Snyder SIX5 ENCSR000BGX r=0.33
K562 Snyder GATA2 ENCSR000EWG r=0.33
K562 Snyder USF2 ENCSR000EHG r=0.33
K562 Snyder RAD21 ENCSR000FAD r=0.32
K562 Snyder ZNF263 ENCSR000EWN r=0.32
K562 Snyder CBX3 ENCSR000ATV r=0.32
K562 Snyder SIRT6 ENCSR000AUB r=0.32
K562 Snyder CREBBP ENCSR000ATT r=0.32
K562 Snyder GATA1 ENCSR000EWM r=0.32
K562 Snyder ZNF274 ENCSR000EVX r=0.32
K562 Snyder MEF2A ENCSR000BNV r=0.31
K562 Snyder EZH2 ENCSR000AQE r=0.30
K562 Snyder BRF2 ENCSR000DOC r=0.30
K562 Snyder NCOR1 ENCSR000ATY r=0.30
K562 Snyder CEBPB ENCSR000EHE r=0.30
K562 Snyder THAP1 ENCSR000BNN r=0.30
K562 Snyder KDM1A ENCSR000ATX r=0.30
K562 Snyder SP2 ENCSR000BNL r=0.29
K562 Snyder YY1 ENCSR000BMH r=0.29
K562 Snyder XRCC4 ENCSR000FAC r=0.29
K562 Snyder CTCF ENCSR000AKO r=0.28
K562 Snyder SP1 ENCSR000BKO r=0.28
K562 Snyder ZBTB33 ENCSR000BKF r=0.28
K562 Snyder CTCFL ENCSR000BNK r=0.28
K562 Snyder HDAC2 ENCSR000BMG r=0.27
K562 Snyder SIX5 ENCSR000BNW r=0.27
K562 Snyder CTCF ENCSR000DWE r=0.27
K562 Snyder SUZ12 ENCSR000AUC r=0.26
K562 Snyder GATA2 ENCSR000BKM r=0.26
K562 Snyder E2F6 ENCSR000BLI r=0.26
K562 Snyder CTCF ENCSR000BPJ r=0.26
K562 Snyder ZBTB7A ENCSR000BME r=0.25
K562 Snyder REST ENCSR000ATM r=0.25
K562 Snyder SETDB1 ENCSR000EWD r=0.25
K562 Snyder RNF2 ENCSR000AUA r=0.25
K562 Snyder CTCF ENCSR000DMA r=0.24
K562 Snyder GTF3C2 ENCSR000DOD r=0.24
K562 Snyder FOSL1 ENCSR000BMV r=0.23
K562 Snyder NR2C2 ENCSR000EWH r=0.23
K562 Snyder NFYB ENCSR000EGQ r=0.22
K562 Snyder CHD4 ENCSR000ATL r=0.20
K562 Snyder RAD21 ENCSR000BKV r=0.20
K562 Snyder UBTF ENCSR000EFZ r=0.19
K562 Snyder CHD1 ENCSR000AQD r=0.19
K562 Snyder BDP1 ENCSR000DOK r=0.18
K562 Snyder UBTF ENCSR000EFW r=0.18
K562 Snyder POLR3G ENCSR000EHQ r=0.15
K562 Snyder CBX2 ENCSR000ATU r=0.14
K562 Snyder BRF1 ENCSR000DOJ r=0.14
K562 Snyder CBX8 ENCSR000ATW r=0.11
K562 Snyder POLR3A ENCSR000DOI r=0.09
K562 Snyder ZNF274 ENCSR000EWE r=-0.02

2,961 peaks (download )

Notes

Peaks (left to right in the heatmap) are sorted by the descending order of [-log10(q-value), -log10(p-value), TF ChIP-seq signal].

Average Profiles of Nucleosomes around the Summit of ChIP-seq Peaks

GM12878 - Snyder - ENCSR000DZB

K562 - Snyder - ENCSR000EFU

Notes

Average nucleosome occupancy profiles in GM12878 and K562 cells are shown for the [-2 kb, +2 kb] window centered on the summits of the TF ChIP-seq peaks, separately for peaks that are proximal to an annotated transcription start site (red lines) and for peaks that are distal to all annotated transcription start sites (blue lines), as defined in the Histone section.